THE XIN JIE CHEN LABORATORY
Mitochondrial Biology, Proteostatic Signaling, and Implications for Muscular, Cardiac and Neuronal Functions During Aging.
The main goal of our laboratory is to learn how mitochondrial damage causes cellular stress, and affects cell fitness and organismal survival. We are particularly interested to learn whether mitochondrial Precursor Overaccumulation Stress (mPOS), a novel cell stress mechanism that we recently discovered, contributes to cell degeneration and affects tissue function in aging-related degenerative diseases. We use yeast, cultured human cells and mouse models in our studies.
MITOCHONDRIAL PRECURSOR OVERACCUMULATION STRESS (MPOS) AND NEURAL AND MUSCULAR DEGENERATIVE DISEASES
July 3, 2019
Our research is generously supported by:
Thanks for your interest in our research. Get in touch with us for any questions or comments regarding our work and publications. We’d love to hear from you.
750 East Adams Street, Syracuse, New York 13210